In the 1981, she migrated to Los Angeles, California where she settled in the Pico-Union district along with the many indigenous-migrant communities in the area. Odilia is the first Zapotec women to be the  General Binational Coordinator of the Frente Indígena de Organizaciones Binacionales/Indigenous Front of Binational Organizations (FIOB), after serving six years (two terms) as Binational Women’s Issues Coordinator of the organization that was created by indigenous migrants in South Central LA in 1991. The Odilia has worked with the FIOB on indigenous peoples rights, human rights and cultural and political education programs for the indigenous-migrant communities. Her organizing knowledge and experience are held in high regard, with multiple academic publications, awards, and lectures in universities across the United States including John Hopkins, USC and UCLA. Her commitment to civic engagement expands beyond her own community; she is a past board member for the Southern California Library, and holds a seat on the finance committee of the multi-ethnic Mexican migrant coalition, RED Mexicana de Líderes Migrantes. She co-wrote, with Maylei Blackwell, Rufino Domínguez ,Laura Velasco and Centolia Maldonado Vázquez, “Genero, generación y equidad, Los retos del liderazgo indígena binacional entre México y Estados Unidos en la experiencia del Frente Indígena de Organizaciones Binacionales (FIOB),” which appears in Otros Saberes: Collaborative Research on Indigenous and Afro-Descendant Cultural Políticas well as  “Indigenous Migrants and Language Barriers in the United States,” published in Diálogo, Center for Latino Research, DePaul University. Her testimonio has been published as: “Mujer rebelde: testimonio de Odilia Romero Hernández.” (“Rebel Woman: Testimony of Odilia Romero Hernandez”) in Desacatos31 (2009).